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The pediatric and adolescent PIOC cases with local recurrence showed poor prognosis. During the follow-up period, local recurrence occurred in three patients. The provisional diagnosis for seven patients was odontogenic cyst and enucleation was performed in six cases including the new case.

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Tooth displacement and root resorption were observed in four and six cases, respectively. The radiologic borders were well-defined in six cases and corticated in four cases. Clinical and radiographic features, diagnosis and treatment approaches, and prognosis were investigated.Īges ranged from 4 to 18 years. A total of 12 pediatric and adolescent cases including 11 PIOCs from the literature and one new case of a 14-year-old female were analyzed. Cases under the age of 20 were classified as pediatric and adolescent populations in this study. In this study, related literatures of pediatric and adolescent PIOC cases were analyzed under strict PRISMA guidelines along with an adolescent case who was provisionally misdiagnosed as an odontogenic cyst.Īll case reports for PIOC published in English from 1966 to 2021 were collected. PIOC can be misdiagnosed as odontogenic cyst because it occasionally shows a well-defined border on radiography. Primary intraosseous carcinoma (PIOC) is a rare malignant odontogenic tumor that predominantly occurs in males older than 50 years. Prognosis masih belum bisa dipastikan.

Primary Intraosseous Carcinoma, Not Otherwise Specified(PIOC, NOS) is an extremely rare neoplasm defined as squamous cell carcinoma in the mandible, presumably from the residue of odontogenic epithelium.








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